{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n DDR1‐AS1 is a long non‐coding RNA that has been implicated in the regulation of the DDR1 gene, which encodes a receptor involved in key cellular activities such as adhesion, extracellular matrix remodeling, and possibly immune modulation. While the provided abstract focused on the application of sequence capture and massively parallel pyrosequencing to comprehensively characterize genetic variation in the human major histocompatibility complex for improved risk assessment in allogeneic hematopoietic stem cell transplantation (1), it does not directly report on DDR1‐AS1. Nonetheless, in the broader context of immunoregulation and transplantation, emerging studies suggest that non‐coding RNAs like DDR1‐AS1 may contribute to the fine‐tuning of immune responses by modulating gene networks involved in cell–cell communication and tolerance mechanisms. A deeper understanding of DDR1‐AS1’s function could provide complementary insights to the genetic analyses described in (1) and potentially refine our approaches to mitigating complications such as graft versus host disease and graft versus leukemia by delineating additional layers of molecular regulation.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Johannes Pröll, Martin Danzer, Stephanie Stabentheiner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Sequence capture and next generation resequencing of the MHC region highlights potential transplantation determinants in HLA identical haematopoietic stem cell transplantation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "DNA Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/dnares/dsr008"}], "href": "https://doi.org/10.1093/dnares/dsr008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21622977"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21622977"}]}]}]}