{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The study demonstrates that the long non‐coding RNA lncRNA‐CTD‑2108O9.1—which may be considered in this context as equivalent to or related to EGFLAM‑AS1—functions as a potent metastasis inhibitor in breast cancer. This RNA is found to be downregulated in breast cancer tissues and cell lines, and its tumor‐suppressive role is executed by targeting the leukemia inhibitory factor receptor (LIFR), a protein known to suppress metastasis. By modulating LIFR activity, lncRNA‑CTD‑2108O9.1 effectively represses metastatic processes, suggesting its potential as both a biomarker and a therapeutic target for limiting breast cancer progression (1)."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mozhi Wang, Mengshen Wang, Zhenning Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long non-coding RNA-CTD-2108O9.1 represses breast cancer metastasis by influencing leukemia inhibitory factor receptor."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cas.13592"}], "href": "https://doi.org/10.1111/cas.13592"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29603493"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29603493"}]}]}]}