{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "This study employs a population-scale biobank with extensive genomic and phenotypic data to perform a comprehensive analysis of genetic associations across more than 2,000 traits using truncated singular value decomposition. The approach successfully identified latent components of genetic variation—thereby shedding light on how specific variants and genes, such as GPR151 and PDE3B, contribute to obesity‐related traits and adipocyte biology (1). Notably, the abstract does not mention the noncoding RNA EML2‑AS1, and thus its function remains uncharacterized in the context of this analysis (1)."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "Citation:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yosuke Tanigawa, Jiehan Li, Johanne M Justesen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-019-11953-9"}], "href": "https://doi.org/10.1038/s41467-019-11953-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31492854"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31492854"}]}]}]}