{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In the study by Walston et al. (1), the genome‐wide investigation focused on genetic factors influencing leisure‐time physical activity (LTPA) rather than providing direct insights into ENO1‐AS1. The authors identified several loci with potential roles in regulating the homeostatic drive coupled with the reward system and in governing the capacity for performing LTPA. Although ENO1‐AS1 is not specifically discussed in this abstract, the work contributes to a broader framework suggesting that noncoding RNA species and other genetic elements may be integral to understanding the biological regulation of activity levels. In this context, if ENO1‐AS1 is later found to be among the candidate loci or linked regulatory elements, it might be hypothesized to similarly influence metabolic or signaling pathways that underlie motivational and regulatory processes related to physical activity."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiaochen Lin, Katie Kei-Hang Chan, Yen-Tsung Huang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic Determinants for Leisure-Time Physical Activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Sci Sports Exerc (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1249/MSS.0000000000001607"}], "href": "https://doi.org/10.1249/MSS.0000000000001607"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29538177"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29538177"}]}]}]}