{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n ENOX1‐AS1 is one of eight immune‐related long non-coding RNAs (irlncRNAs) incorporated into a prognostic signature for small‐cell lung cancer (SCLC)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In the referenced study, this composite irlncRNA panel was able to stratify patients into distinct risk groups, with low‐risk individuals exhibiting an activated immune phenotype and improved responses to chemotherapy. Although the precise biological function of ENOX1‐AS1 was not detailed, its inclusion in the signature implies a role in modulating tumor immunity and possibly influencing the tumor microenvironment. Consequently, ENOX1‐AS1, as part of this molecular classifier, holds potential as a biomarker for predicting treatment outcomes and guiding therapeutic decisions in SCLC.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Zhihui Zhang, Yuejun Luo, Chaoqi Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An immune-related lncRNA signature predicts prognosis and adjuvant chemotherapeutic response in patients with small-cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Cell Int (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12935-021-02357-1"}], "href": "https://doi.org/10.1186/s12935-021-02357-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34930244"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34930244"}]}]}]}