ERCC6-PGBD3 Gene

Name ERCC6-PGBD3 readthrough
Description This locus represents naturally-occurring readthrough transcription between the neighboring ERCC6 (excision repair cross-complementing rodent repair deficiency, complementation group 6) and PGBD (piggyBac transposable element derived 3) genes on chromosome 10. The readthrough transcripts encode a fusion protein that shares sequence with the product of each individual gene. The encoded protein may function in DNA repair and in the innate immune response. It binds to MER85 sequences in DNA, and may interact with transcription factors to modulate gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Synonyms CPFP, CSB-PGBD3
NCBI Gene ID 101243544
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Predicted Functions View ERCC6-PGBD3's ARCHS4 Predicted Functions.
Co-expressed Genes View ERCC6-PGBD3's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View ERCC6-PGBD3's ARCHS4 Predicted Functions.

Functional Associations

ERCC6-PGBD3 has 52 functional associations with biological entities spanning 5 categories (chemical, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 8 datasets.

Click the + buttons to view associations for ERCC6-PGBD3 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of ERCC6-PGBD3 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of ERCC6-PGBD3 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of ERCC6-PGBD3 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of ERCC6-PGBD3 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of ERCC6-PGBD3 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for ERCC6-PGBD3 protein from the InterPro Predicted Protein Domain Annotations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain ERCC6-PGBD3 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of ERCC6-PGBD3 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.