{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n ERICH3‐AS1 is a long non‐coding RNA that has emerged as a potential prognostic biomarker in gastric cancer. Analysis of The Cancer Genome Atlas data revealed that ERICH3‐AS1 is significantly up‐regulated in gastric cancer tissues, and higher expression levels are associated with both earlier recurrence and poorer patient outcomes. Specifically, ERICH3‐AS1 has been identified as an independent risk factor for disease‐free survival, suggesting that it may play a role in tumor progression or recurrence mechanisms."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Moreover, when integrated into multi‐lncRNA prognostic signatures, ERICH3‐AS1 contributes to models that reliably stratify patients into distinct mortality risk groups, thereby aiding in individualized treatment planning and clinical decision making."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Although its precise molecular function remains to be fully elucidated, the consistent association between elevated ERICH3‐AS1 expression and adverse clinical outcomes underscores its potential importance in gastric cancer biology.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Qiongyun Chen, Xiaoqing Huang, Xuan Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long non-coding RNA ERICH3-AS1 is an unfavorable prognostic factor for gastric cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PeerJ (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7717/peerj.8050"}], "href": "https://doi.org/10.7717/peerj.8050"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32025363"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32025363"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Minggu Zhu, Qicai Wang, Zhaowen Luo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Development and validation of a prognostic signature for preoperative prediction of overall survival in gastric cancer patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Onco Targets Ther (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2147/OTT.S181741"}], "href": "https://doi.org/10.2147/OTT.S181741"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30584329"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30584329"}]}]}]}