FAM224B Gene

Name family with sequence similarity 224, member B (non-protein coding)
Description This locus is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In the current literature provided, there is no functional data or discussion regarding FAM224B. One study addressing alcohol-induced organ damage and the role of microRNAs in mediating such injuries does not include any mention or analysis of FAM224B."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Similarly, an investigation into Y chromosome deletions associated with male infertility and their clinical implications makes no reference to FAM224B."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Thus, based on these abstracts, the biological function of FAM224B remains uncharacterized, and further targeted research is needed to elucidate its role, if any, in the contexts of alcohol-related pathology or reproductive health.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Sathish Kumar Natarajan, Joseph M Pachunka, Justin L Mott "}, {"type": "b", "children": [{"type": "t", "text": "Role of microRNAs in Alcohol-Induced Multi-Organ Injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomolecules (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/biom5043309"}], "href": "https://doi.org/10.3390/biom5043309"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26610589"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26610589"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Stacy Colaco, Deepak Modi "}, {"type": "b", "children": [{"type": "t", "text": "Genetics of the human Y chromosome and its association with male infertility."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Reprod Biol Endocrinol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12958-018-0330-5"}], "href": "https://doi.org/10.1186/s12958-018-0330-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29454353"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29454353"}]}]}]}
Synonyms NCRNA00230B, LINC00230B
NCBI Gene ID 401629
API
Download Associations
Predicted Functions View FAM224B's ARCHS4 Predicted Functions.
Co-expressed Genes View FAM224B's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View FAM224B's ARCHS4 Predicted Functions.

Functional Associations

FAM224B has 257 functional associations with biological entities spanning 3 categories (molecular profile, cell line, cell type or tissue, gene, protein or microRNA) extracted from 6 datasets.

Click the + buttons to view associations for FAM224B from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of FAM224B gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of FAM224B gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of FAM224B gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of FAM224B gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of FAM224B gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of FAM224B gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.