| Name | FGF12 antisense RNA 2 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n FGF12‐AS2 is a long noncoding RNA that has emerged as a promising prognostic biomarker and potential therapeutic target across several cancer types. In clear cell renal carcinoma, FGF12‐AS2 was identified as part of an RNA regulatory network that correlates with tumor stage and patient survival, suggesting a role in disease progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In glioblastoma, incorporation of FGF12‐AS2 into a risk prediction model highlights its potential relevance in tumor pathogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Functional studies in non‐small cell lung carcinoma (NSCLC) further demonstrated that FGF12‐AS2 promotes tumorigenesis by sponging miR‑188‑3p, thereby upregulating NCAPG2 and facilitating cell proliferation, migration, invasion, and the epithelial‐to‐mesenchymal transition."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Moreover, FGF12‐AS2 consistently appears in ceRNA network analyses and prognostic signatures in NSCLC and lung adenocarcinoma, underscoring its association with overall survival and its involvement in tumor molecular circuitry."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "6"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Wenjun Lu, Hengchen Liu, Xin Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A ceRNA Network Composed of Survival-Related lncRNAs, miRNAs, and mRNAs in Clear Cell Renal Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Comput Math Methods Med (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2022/8504441"}], "href": "https://doi.org/10.1155/2022/8504441"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35529267"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35529267"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xiaomin Li, Rui Chen, Ci Ren, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Systematic analysis of the long noncoding RNA (lncRNA)-miRNA-mRNA competing endogenous RNA network to identify prognostic biomarkers and the potential regulatory axis in glioblastoma multiforme."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Transl Cancer Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21037/tcr-21-1162"}], "href": "https://doi.org/10.21037/tcr-21-1162"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35116328"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35116328"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Lili Zhou, Chen Xing, Dongxia Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Downregulation of lncRNA FGF12-AS2 suppresses the tumorigenesis of NSCLC via sponging miR-188-3p."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Open Med (Wars) (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1515/med-2020-0219"}], "href": "https://doi.org/10.1515/med-2020-0219"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33344773"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33344773"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Xiaoyuan Wang, Hang Yin, Luquan Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Thorac Dis (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21037/jtd.2019.05.69"}], "href": "https://doi.org/10.21037/jtd.2019.05.69"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31285869"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31285869"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yan Chen, Xiuxiu Zhang, Jinze Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Immune-related eight-lncRNA signature for improving prognosis prediction of lung adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Lab Anal (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcla.24018"}], "href": "https://doi.org/10.1002/jcla.24018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34550610"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34550610"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Huaihui Tang, Zhongshuai Wang, Qianqian Shao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive Analysis of Competing Endogenous RNA (ceRNA) Network Based on RNAs Differentially Expressed in Lung Adenocarcinoma Using The Cancer Genome Atlas (TCGA) Database."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Sci Monit (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.12659/MSM.922676"}], "href": "https://doi.org/10.12659/MSM.922676"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32533823"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32533823"}]}]}]}
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| NCBI Gene ID | 100873987 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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FGF12-AS2 has 5 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 1 datasets.
Click the + buttons to view associations for FGF12-AS2 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of FGF12-AS2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |