| Name | uncharacterized LOC400533 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a recent study investigating the competitive endogenous RNA (ceRNA) regulatory networks in lung adenocarcinoma (LUAD), FLJ26245 was identified as one of several ceRNAs significantly associated with overall patient survival."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Although the precise molecular mechanism of FLJ26245 remains to be fully elucidated, its inclusion in the ceRNA network—alongside FAM83A, miR-34c-5p, and KCNQ1OT1—suggests that it may play a role in modulating gene expression relevant to LUAD oncogenesis and progression. Moreover, given that FAM83A has also been implicated in drug resistance, these findings underscore the potential of FLJ26245 as a prognostic biomarker and a candidate for targeted therapies in LUAD.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yuanyong Wang, Tong Lu, Yang Wo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a putative competitive endogenous RNA network for lung adenocarcinoma using TCGA datasets."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PeerJ (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7717/peerj.6809"}], "href": "https://doi.org/10.7717/peerj.6809"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31065463"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31065463"}]}]}]}
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| Synonyms | LINC02167 |
| NCBI Gene ID | 400533 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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FLJ26245 has 217 functional associations with biological entities spanning 4 categories (molecular profile, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for FLJ26245 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ26245 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ26245 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at FLJ26245 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of FLJ26245 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of FLJ26245 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of FLJ26245 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ26245 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of FLJ26245 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain FLJ26245 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of FLJ26245 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at FLJ26245 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |