FLJ30679 Gene

Name uncharacterized protein FLJ30679
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n FLJ30679 is a transcript that currently lacks a clearly defined biological function. In one study investigating gene expression in diabetic foot ulcers, FLJ30679 was identified as one of several long non‐coding RNAs that were significantly up‐regulated in affected tissues; bioinformatics analyses of co‐expression networks suggested that these lncRNAs—including FLJ30679—may be involved in key processes such as ERK1/2 cascade regulation, secondary alcohol biosynthesis, centrosome duplication, and DNA repair."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In another genome‐wide profiling study of IgA nephropathy, FLJ30679 was noted among approximately 35% of altered gene expressions that were annotated only as hypothetical proteins or lacked a conventional gene title, highlighting that its function remains to be elucidated in the context of renal pathology."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Collectively, while FLJ30679 appears to be dysregulated in both diabetic foot ulcers and IgA nephropathy, further functional studies are needed to determine its precise role in disease pathogenesis.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Pijun Yu, Jian Guo, Junjie Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Co-expression network analysis revealing the key lncRNAs in diabetic foot ulcers."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arch Med Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5114/aoms.2019.84699"}], "href": "https://doi.org/10.5114/aoms.2019.84699"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31572456"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31572456"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Keng Thye Woo, Yeow Kok Lau, Yi Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Urotensin 2 and retinoic acid receptor alpha (RARA) gene expression in IgA nephropathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Ann Acad Med Singap (2010)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20957306"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20957306"}]}]}]}
NCBI Gene ID 146512
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Predicted Functions View FLJ30679's ARCHS4 Predicted Functions.
Co-expressed Genes View FLJ30679's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View FLJ30679's ARCHS4 Predicted Functions.

Functional Associations

FLJ30679 has 1,540 functional associations with biological entities spanning 6 categories (molecular profile, organism, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for FLJ30679 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of FLJ30679 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles tissues with high or low expression of FLJ30679 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of FLJ30679 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of FLJ30679 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of FLJ30679 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of FLJ30679 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of FLJ30679 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at FLJ30679 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of FLJ30679 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of FLJ30679 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of FLJ30679 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of FLJ30679 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of FLJ30679 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of FLJ30679 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of FLJ30679 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of FLJ30679 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of FLJ30679 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of FLJ30679 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of FLJ30679 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of FLJ30679 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at FLJ30679 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of FLJ30679 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.