| Name | uncharacterized LOC100192420 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n FLJ41941 is a long non‐coding RNA that has emerged as a potential prognostic biomarker in cancer. In a study focusing on oral squamous cell carcinoma (OSCC), FLJ41941 was identified among a panel of six differentially expressed lncRNAs that were significantly associated with overall survival, suggesting it may play a role within the competing endogenous RNA (ceRNA) regulatory network that influences key oncogenic pathways such as ECM–receptor interactions, cytokine–cytokine receptor interactions, focal adhesion, arachidonic acid metabolism, and p53 signaling (2). Although the study of lung adenocarcinoma survival outcomes did not specifically investigate FLJ41941, its broader inclusion among transcriptomically derived prognostic markers underscores the potential importance of such lncRNAs in precision oncology, where transcriptomic data can provide powerful insights into patient prognosis (1).\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Together, these results highlight FLJ41941 as a promising candidate for further functional characterization, with its dysregulated expression potentially impacting cancer progression and patient survival.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " (2)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Fei Deng, Lanlan Shen, He Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Classify multicategory outcome in patients with lung adenocarcinoma using clinical, transcriptomic and clinico-transcriptomic data: machine learning versus multinomial models."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Cancer Res (2020)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33415023"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33415023"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Simin Li, Xiujie Chen, Xiangqiong Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Complex integrated analysis of lncRNAs-miRNAs-mRNAs in oral squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oral Oncol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.oraloncology.2017.07.026"}], "href": "https://doi.org/10.1016/j.oraloncology.2017.07.026"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28939059"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28939059"}]}]}]}
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| Synonyms | LINC01634 |
| NCBI Gene ID | 100192420 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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FLJ41941 has 465 functional associations with biological entities spanning 3 categories (molecular profile, cell line, cell type or tissue, gene, protein or microRNA) extracted from 12 datasets.
Click the + buttons to view associations for FLJ41941 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ41941 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of FLJ41941 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of FLJ41941 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ41941 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at FLJ41941 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of FLJ41941 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of FLJ41941 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of FLJ41941 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of FLJ41941 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of FLJ41941 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at FLJ41941 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of FLJ41941 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |