{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a recent study (1), a panel of nine testis‐specific extracellular vesicle long noncoding RNAs (lncRNAs) was developed to noninvasively predict the presence of testicular spermatozoa in patients with nonobstructive azoospermia. Among these, GABRG3‐AS1 was identified as one of the differentially expressed lncRNAs incorporated into the biomarker panel. Although the study did not specifically delineate the individual biological function or regulatory mechanism of GABRG3‐AS1 in spermatogenesis, its inclusion in the panel underscores its potential association with testicular function and sperm production. The combined expression profiles of these lncRNAs, including GABRG3‐AS1, not only allowed for high sensitivity and specificity in predicting successful sperm retrieval but also demonstrated superiority over conventional serum hormone models. The authors emphasize that the precise regulatory roles of these lncRNAs, GABRG3‐AS1 among them, remain to be elucidated in future research.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yun Xie, Jiahui Yao, Xinzong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A panel of extracellular vesicle long noncoding RNAs in seminal plasma for predicting testicular spermatozoa in nonobstructive azoospermia patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Reprod (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/humrep/deaa184"}], "href": "https://doi.org/10.1093/humrep/deaa184"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32914196"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32914196"}]}]}]}