HACL2 Gene

Name 2-hydroxyacyl-CoA lyase 2
NCBI Gene ID 10994
API
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Predicted Functions View HACL2's ARCHS4 Predicted Functions.
Co-expressed Genes View HACL2's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View HACL2's ARCHS4 Predicted Functions.

Functional Associations

HACL2 has 587 functional associations with biological entities spanning 5 categories (chemical, functional term, phrase or reference, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 9 datasets.

Click the + buttons to view associations for HACL2 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of HACL2 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
Carcinogenome Chemical Perturbation Carcinogenicity Signatures small molecule perturbations changing expression of HACL2 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of HACL2 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
CM4AI U2OS Cell Map Protein Localization Assemblies assemblies containing HACL2 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
GWAS Catalog SNP-Phenotype Associations 2025 phenotypes associated with HACL2 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of HACL2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of HACL2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of HACL2 gene from the Rummagene Transcription Factor Associations 2026 dataset.
Sci-Plex Drug Perturbation Signatures drug perturbations changing expression of HACL2 gene from the Sci-Plex Drug Perturbation Signatures dataset.