| Name | HECW1 intronic transcript 1 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe provided abstract (1) focused on elucidating genetic causes of premature ovarian insufficiency through whole exome sequencing and subsequent identification of candidate variants in genes central to DNA damage repair and meiosis—for example, REC8 and HROB—as well as other factors such as MCM8, NUP107, STAG3, HFM1, and POF1B. Notably, the long non‐coding transcript HECW1‐IT1 was not specifically mentioned or functionally described in the study. Thus, based on this abstract, no functional insights regarding HECW1‐IT1 are available, and its role in ovarian physiology or pathogenesis remains to be elucidated by future research."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Elena J Tucker, Katrina M Bell, Gorjana Robevska, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Meiotic genes in premature ovarian insufficiency: variants in HROB and REC8 as likely genetic causes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Hum Genet (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41431-021-00977-9"}], "href": "https://doi.org/10.1038/s41431-021-00977-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34707299"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34707299"}]}]}]}
|
| NCBI Gene ID | 100127950 |
| API | |
| Download Associations | |
| Predicted Functions |
![]() |
| Co-expressed Genes |
![]() |
| Expression in Tissues and Cell Lines |
![]() |
HECW1-IT1 has 148 functional associations with biological entities spanning 4 categories (disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 7 datasets.
Click the + buttons to view associations for HECW1-IT1 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of HECW1-IT1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of HECW1-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of HECW1-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of HECW1-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of HECW1-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of HECW1-IT1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of HECW1-IT1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |