HS3ST3B1 Gene

HGNC Family	Sulfotransferases
Name	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
Description	The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n HS3ST3B1 is a heparan sulfate 3‐O‐sulfotransferase that catalyzes the 3‐O‐sulfation of glucosamine residues during the late stages of heparan sulfate (HS) biosynthesis, thereby generating specialized HS structures that modulate protein–ligand interactions and downstream signaling. In immune cells, HS3ST3B1 contributes to the formation of specific HS motifs that regulate interactions with extracellular ligands, influencing lymphocyte migration and activation, as demonstrated by its predominant expression in peripheral T cells and involvement in natural killer cell receptor regulation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In monocytes, its transcription is rapidly induced upon Toll-like receptor stimulation, suggesting a role in tailoring HS fine structure for the regulation of inflammatory and immune responses."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " HS3ST3B1 also exhibits antiviral properties; overexpression in hepatocytes results in inhibition of hepatitis B virus replication and reduction of viral RNA levels, effects that are reversed upon gene silencing."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": " Moreover, deregulated HS3ST3B1 expression has been linked to cancer progression. Enhanced levels of this enzyme promote epithelial-to-mesenchymal transition (EMT) in pancreatic and non–small cell lung cancers, an effect associated with increased expression of EMT regulators such as Snail."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " In bladder cancer, HS3ST3B1 is posttranscriptionally regulated via interactions with microRNAs (e.g., miR-218-5p and miR-99b), which modify its expression and thereby affect tumor cell proliferation, invasion, and chemoresistance."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": " Genetic studies further implicate HS3ST3B1 in host–pathogen interactions; polymorphisms in its gene are associated with altered susceptibility to Plasmodium falciparum parasitaemia"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": "while its activity is linked to enhanced vascular endothelial growth factor shedding and acute myeloid leukemia progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": " In developmental contexts, modulation of HS3ST3B1 activity influences cell fate decisions, as illustrated by its role in restricting ureteric bud outgrowth during kidney formation"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": ", and loss-of-function studies in haploid epiblast stem cells suggest that HS3ST3B1 attenuation can facilitate reprogramming to the ground state."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Christophe Vanpouille, Audrey Deligny, Maryse Delehedde, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M701835200"}], "href": "https://doi.org/10.1074/jbc.M701835200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17588944"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17588944"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Michael Brusilovsky, Moti Cordoba, Benyamin Rosental, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1302079"}], "href": "https://doi.org/10.4049/jimmunol.1302079"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24127555"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24127555"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Anne-Sophie Sikora, Maxime Delos, Pierre Martinez, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of the Expression of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) by Inflammatory Stimuli in Human Monocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.25444"}], "href": "https://doi.org/10.1002/jcb.25444"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26575945"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26575945"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Zhenzhen Zhang, Xiang Liu, Juan Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Heparin sulphate D-glucosaminyl 3-O-sulfotransferase 3B1 plays a role in HBV replication."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Virology (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.virol.2010.07.030"}], "href": "https://doi.org/10.1016/j.virol.2010.07.030"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20705311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20705311"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Huai-Bin Su, Qiang Luo, Zhen-Zhen Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[Down-regulation of hepatitis B virus replication by heparin sulfate-D-glucosaminyl-3-O-sulfotransferase 3B1]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Gan Zang Bing Za Zhi (2011)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22053370"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22053370"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Kai Song, Qin Li, Zhen-Zhen Jiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biol Ther (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/cbt.12.5.15957"}], "href": "https://doi.org/10.4161/cbt.12.5.15957"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21709440"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21709440"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Zengli Zhang, Hanyi Jiang, Yongsheng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Heparan sulfate D-glucosamine 3-O-sulfotransferase 3B1 is a novel regulator of transforming growth factor-beta-mediated epithelial-to-mesenchymal transition and regulated by miR-218 in nonsmall cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer Res Ther (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4103/jcrt.JCRT_659_17"}], "href": "https://doi.org/10.4103/jcrt.JCRT_659_17"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29516954"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29516954"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Yongzhi Li, Benkang Shi, Fengming Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA KCNQ1OT1 facilitates the progression of bladder cancer by targeting MiR-218-5p/HS3ST3B1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Gene Ther (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41417-020-00211-6"}], "href": "https://doi.org/10.1038/s41417-020-00211-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32820233"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32820233"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Yongzhi Li, Benkang Shi, Fengming Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long Non-coding RNA DLEU1 Promotes Cell Proliferation, Invasion, and Confers Cisplatin Resistance in Bladder Cancer by Regulating the miR-99b/HS3ST3B1 Axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fgene.2019.00280"}], "href": "https://doi.org/10.3389/fgene.2019.00280"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30984249"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30984249"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Alexandre Atkinson, Séverine Garnier, Sarwat Afridi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Malar J (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1475-2875-11-108"}], "href": "https://doi.org/10.1186/1475-2875-11-108"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22475533"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22475533"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Ngoc Thy Nguyen, Romain R Vivès, Magali Torres, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Glycobiology (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/glycob/cwy038"}], "href": "https://doi.org/10.1093/glycob/cwy038"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29718295"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29718295"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Lei Zhang, Kai Song, Ling Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1 (HS3ST3B1) promotes angiogenesis and proliferation by induction of VEGF in acute myeloid leukemia cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.25066"}], "href": "https://doi.org/10.1002/jcb.25066"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25536282"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25536282"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Elisabeth A Rutledge, Andrew P McMahon "}, {"type": "b", "children": [{"type": "t", "text": "Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Dyn (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/dvdy.157"}], "href": "https://doi.org/10.1002/dvdy.157"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32017326"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32017326"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Qian Gao, Wenhao Zhang, Yiding Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High-throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Transl Med (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/sctm.20-0468"}], "href": "https://doi.org/10.1002/sctm.20-0468"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33511777"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33511777"}]}]}]}
Synonyms	3OST3B1, 3-OST-3B, H3-OST-3B
Proteins	HS3SB_HUMAN
NCBI Gene ID	9953
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

HS3ST3B1 has 4,739 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 107 datasets.

Click the + buttons to view associations for HS3ST3B1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

HS3ST3B1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by HS3ST3B1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HS3ST3B1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of HS3ST3B1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of HS3ST3B1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of HS3ST3B1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HS3ST3B1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of HS3ST3B1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HS3ST3B1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HS3ST3B1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of HS3ST3B1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of HS3ST3B1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of HS3ST3B1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with HS3ST3B1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HS3ST3B1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of HS3ST3B1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of HS3ST3B1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of HS3ST3B1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing HS3ST3B1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing HS3ST3B1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with HS3ST3B1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with HS3ST3B1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of HS3ST3B1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with HS3ST3B1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with HS3ST3B1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with HS3ST3B1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by HS3ST3B1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with HS3ST3B1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with HS3ST3B1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with HS3ST3B1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at HS3ST3B1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HS3ST3B1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of HS3ST3B1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing HS3ST3B1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with HS3ST3B1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with HS3ST3B1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of HS3ST3B1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with HS3ST3B1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing HS3ST3B1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of HS3ST3B1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of HS3ST3B1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.