HTR2A Gene

HGNC Family	5-hydroxytryptamine (serotonin) receptors (HTR), G protein-coupled receptors
Name	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
Description	This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The serotonin 2A receptor, encoded by the HTR2A gene, is a pivotal G protein–coupled receptor mediating diverse serotonergic actions in both the central nervous system and peripheral tissues. In the brain, HTR2A modulates neural excitability and synaptic plasticity—for instance, by contributing to excitatory responses in cortical pyramidal neurons and regulating behavioral outputs such as mood, fear, and cognition."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": " Genetic and epigenetic studies have consistently implicated HTR2A variation in several neuropsychiatric conditions including major depression, schizophrenia, bipolar disorder, and attention‐deficit/hyperactivity disorder; in these studies, HTR2A variants or differential methylation patterns have been linked to both disease susceptibility and modulation of treatment response, such as variations in antidepressant efficacy and tolerability."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "10"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n At a mechanistic level, experimental studies have delineated key elements underpinning HTR2A receptor activation and signaling. Specific structural determinants—such as ionic interactions between conserved residues—are critical for proper receptor activation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Moreover, interactions with scaffolding proteins, including caveolin‐1 and PDZ domain–containing partners, have been shown to regulate receptor intracellular trafficking and the strength of downstream signaling."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In addition, HTR2A is the key target for several hallucinogenic agents that trigger receptor-mediated excitatory responses; behavioral studies have demonstrated that activation of 5‑HT2A receptors contributes to alterations in locomotor activity and fear responses."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}, {"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Beyond its neural functions, HTR2A also participates in peripheral processes such as vascular smooth muscle regulation and the promotion of mucosal growth in the gastrointestinal system, as indicated by studies showing that antagonism of 5‑HT2A receptors modulates cellular proliferation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these findings support a multifaceted role for HTR2A in serotonergic neurotransmission. Its genetic and functional variability not only contributes to differences in individual responses to pharmacotherapies (such as SSRIs) but also underlies susceptibility to various psychiatric disorders, ultimately positioning HTR2A as a key mediator in both central and peripheral serotonergic signaling."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "9"}, {"type": "fg_f", "ref": "13"}, {"type": "fg_f", "ref": "16"}, {"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mercè Amargós-Bosch, Analía Bortolozzi, M Victoria Puig, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cereb Cortex (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/cercor/bhg128"}], "href": "https://doi.org/10.1093/cercor/bhg128"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14754868"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14754868"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "David A Shapiro, Kurt Kristiansen, David M Weiner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111675200"}], "href": "https://doi.org/10.1074/jbc.M111675200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11801601"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11801601"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Tomoko Isosaka, Tomohiko Matsuo, Takashi Yamaguchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Htr2a-Expressing Cells in the Central Amygdala Control the Hierarchy between Innate and Learned Fear."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cell.2015.10.047"}], "href": "https://doi.org/10.1016/j.cell.2015.10.047"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26590419"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26590419"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "T C Eley, K Sugden, A Corsico, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gene-environment interaction analysis of serotonin system markers with adolescent depression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Psychiatry (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.mp.4001546"}], "href": "https://doi.org/10.1038/sj.mp.4001546"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15241435"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15241435"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "M Kato, A Serretti "}, {"type": "b", "children": [{"type": "t", "text": "Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Psychiatry (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/mp.2008.116"}], "href": "https://doi.org/10.1038/mp.2008.116"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18982004"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18982004"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Francis J McMahon, Silvia Buervenich, Dennis Charney, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1086/503820"}], "href": "https://doi.org/10.1086/503820"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16642436"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16642436"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "C Minov, T C Baghai, C Schüle, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurosci Lett (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0304-3940(01)01704-9"}], "href": "https://doi.org/10.1016/s0304-3940(01"}, {"type": "t", "text": "01704-9) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11311507"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11311507"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Hamid Mostafavi Abdolmaleky, Stephen V Faraone, Stephen J Glatt, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Meta-analysis of association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Schizophr Res (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0920-9964(03)00183-x"}], "href": "https://doi.org/10.1016/s0920-9964(03"}, {"type": "t", "text": "00183-x) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14741324"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14741324"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Hamid Mostafavi Abdolmaleky, Sahab Yaqubi, Panagiotis Papageorgis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Schizophr Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.schres.2011.04.007"}], "href": "https://doi.org/10.1016/j.schres.2011.04.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21550210"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21550210"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "M Ribasés, J A Ramos-Quiroga, A Hervás, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Exploration of 19 serotoninergic candidate genes in adults and children with attention-deficit/hyperactivity disorder identifies association for 5HT2A, DDC and MAOB."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Psychiatry (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.mp.4002100"}], "href": "https://doi.org/10.1038/sj.mp.4002100"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17938636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17938636"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Anushree Bhatnagar, Douglas J Sheffler, Wesley K Kroeze, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M404673200"}], "href": "https://doi.org/10.1074/jbc.M404673200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15190056"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15190056"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Carine Bécamel, Sophie Gavarini, Benjamin Chanrion, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M312106200"}], "href": "https://doi.org/10.1074/jbc.M312106200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14988405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14988405"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Adam L Halberstadt, Iris van der Heijden, Michael A Ruderman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuropsychopharmacology (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/npp.2009.29"}], "href": "https://doi.org/10.1038/npp.2009.29"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19322172"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19322172"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Qian Li, Christine H Wichems, Li Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurochem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1046/j.1471-4159.2003.01607.x"}], "href": "https://doi.org/10.1046/j.1471-4159.2003.01607.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12614326"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12614326"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Erica R Gross, Michael D Gershon, Kara G Margolis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Neuronal serotonin regulates growth of the intestinal mucosa in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gastroenterology (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1053/j.gastro.2012.05.007"}], "href": "https://doi.org/10.1053/j.gastro.2012.05.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22609381"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22609381"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Mark A Mintun, Yvette I Sheline, Stephen M Moerlein, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: in vivo measurement with [18F]altanserin positron emission tomography."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Psychiatry (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.biopsych.2003.08.015"}], "href": "https://doi.org/10.1016/j.biopsych.2003.08.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14744461"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14744461"}]}]}]}
Synonyms	5-HT2A, HTR2
Proteins	5HT2A_HUMAN
NCBI Gene ID	3356
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

HTR2A has 7,792 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 112 datasets.

Click the + buttons to view associations for HTR2A from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

HTR2A Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HTR2A gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of HTR2A gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of HTR2A gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of HTR2A gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of HTR2A gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of HTR2A gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of HTR2A gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HTR2A gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of HTR2A gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of HTR2A gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of HTR2A gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of HTR2A gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with HTR2A gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HTR2A gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of HTR2A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of HTR2A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of HTR2A gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing HTR2A protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing HTR2A protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with HTR2A protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with HTR2A protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of HTR2A gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with HTR2A gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with HTR2A gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with HTR2A gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by HTR2A gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving HTR2A gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with HTR2A gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with HTR2A gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with HTR2A gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with HTR2A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with HTR2A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for HTR2A protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at HTR2A gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of HTR2A gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of HTR2A gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GAD Gene-Disease Associations	diseases associated with HTR2A gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with HTR2A gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of HTR2A gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with HTR2A gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.