{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In the study described in"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", the primary focus was on identifying genetic determinants of plasma homocysteine levels in subjects of African ancestry. This work highlighted significant associations with known genes such as CBS and CD2AP, and implicated key pathways including GABA receptor activation in the context of neurodegeneration. Notably, the abstract does not mention or provide any information on the function of JRKL‐AS1. Consequently, based on the data presented in this report, no direct role or mechanism for JRKL‐AS1 in modulating homocysteine metabolism, neural signaling, or related physiological processes can be inferred. Further functional studies would be required to determine whether JRKL‐AS1 has any involvement in these or other cellular pathways.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Sungeun Kim, Kwangsik Nho, Vijay K Ramanan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Alzheimers Dis (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3233/JAD-150651"}], "href": "https://doi.org/10.3233/JAD-150651"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26519441"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26519441"}]}]}]}