{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a study aimed at establishing a robust prognostic and diagnostic tool for papillary thyroid cancer (PTC), a nine‐lncRNA signature was identified, which includes KIZ-AS1 as one of its hub components."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Within this signature, KIZ-AS1 is implicated in the molecular regulatory network that contributes to PTC development, with its expression levels closely correlated with the distribution of tumor-infiltrating immune cells. Functional enrichment analyses of the signature suggest that KIZ-AS1, along with the other lncRNAs, may influence key biological processes and signaling pathways involved in tumor progression and immune modulation. These findings indicate that KIZ-AS1 could serve as a potential biomarker for PTC prognosis and diagnosis, ultimately assisting in the stratification of patients and the customization of therapeutic strategies.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jin-Ming Yao, Jun-Yu Zhao, Fang-Fang Lv, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Potential Nine-lncRNAs Signature Identification and Nomogram Diagnostic Model Establishment for Papillary Thyroid Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Oncol Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/pore.2022.1610012"}], "href": "https://doi.org/10.3389/pore.2022.1610012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35280112"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35280112"}]}]}]}