HGNC Family | Keratin associated proteins (KRTAP) |
Name | keratin associated protein 10-1 |
Description | This gene encodes a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This gene encodes a member of the high sulfur KAP family. It is localized to a cluster of intronless KAPs at 21q22.3 which are located within the introns of the C21orf29 gene. [provided by RefSeq, Jul 2008] |
Synonyms | KAP18-1, KAP18.1, KRTAP10.1, KAP10.1, KRTAP18.1, KRTAP18-1 |
Proteins | KR101_HUMAN |
NCBI Gene ID | 386677 |
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Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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KRTAP10-1 has 758 functional associations with biological entities spanning 6 categories (molecular profile, organism, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 32 datasets.
Click the + buttons to view associations for KRTAP10-1 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP10-1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of KRTAP10-1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP10-1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of KRTAP10-1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
CHEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of KRTAP10-1 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
CHEA Transcription Factor Targets | transcription factors binding the promoter of KRTAP10-1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
CHEA Transcription Factor Targets 2022 | transcription factors binding the promoter of KRTAP10-1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing KRTAP10-1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of KRTAP10-1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
COSMIC Cell Line Gene Mutation Profiles | cell lines with KRTAP10-1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
DepMap CRISPR Gene Dependency | cell lines with fitness changed by KRTAP10-1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at KRTAP10-1 gene from the ENCODE Histone Modification Site Profiles dataset. | |
ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of KRTAP10-1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
ENCODE Transcription Factor Targets | transcription factors binding the promoter of KRTAP10-1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with KRTAP10-1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of KRTAP10-1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of KRTAP10-1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
GO Cellular Component Annotations | cellular components containing KRTAP10-1 protein from the curated GO Cellular Component Annotations dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of KRTAP10-1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of KRTAP10-1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of KRTAP10-1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
InterPro Predicted Protein Domain Annotations | protein domains predicted for KRTAP10-1 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of KRTAP10-1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of KRTAP10-1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain KRTAP10-1 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of KRTAP10-1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of KRTAP10-1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at KRTAP10-1 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of KRTAP10-1 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of KRTAP10-1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of KRTAP10-1 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of KRTAP10-1 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |