{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a high‐resolution mapping of the ciliary protein network, a broad range of proteins—including members of key transport and structural complexes—were identified and linked to ciliary proteostasis and signaling (1). Although the study primarily focused on dissecting the roles of ciliary proteins within vesicle trafficking, the cytoskeleton, and ubiquitination pathways, the inclusion of KRTAP20‑3 among the 1,319 identified interactors suggests that this keratin‐associated protein may also contribute to the structural or regulatory integrity of cilia. While KRTAP20‑3 is traditionally recognized in contexts outside of ciliary biology, its presence in this interactome implies a potential, yet uncharacterized, role in interfacing with ciliary signaling or cytoskeletal dynamics. These findings warrant further investigation into whether KRTAP20‑3 participates directly in ciliogenesis or cilia‐related proteostasis, thereby possibly linking keratin‐associated pathways to the molecular mechanisms underlying ciliary function and associated genetic disorders (1).\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An organelle-specific protein landscape identifies novel diseases and molecular mechanisms."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms11491"}], "href": "https://doi.org/10.1038/ncomms11491"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27173435"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27173435"}]}]}]}