LGTN Gene

Name ligatin
Description Ligatin is a peripheral membrane protein found in mammalian and avian tissues during embryonic development and in early differentiated states. It is a receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery where they participate in specific metabolic processes, as well as intercellular adhesion. Ligatin is, therefore, a trafficking receptor for phosphoglycoproteins (summary by Jakoi et al., 1989 [PubMed 2482295]).[supplied by OMIM, Jan 2011]
NCBI Gene ID 100529141
API
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Predicted Functions View LGTN's ARCHS4 Predicted Functions.
Co-expressed Genes View LGTN's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LGTN's ARCHS4 Predicted Functions.

Functional Associations

LGTN has 678 functional associations with biological entities spanning 7 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 29 datasets.

Click the + buttons to view associations for LGTN from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
BioGPS Cell Line Gene Expression Profiles cell lines with high or low expression of LGTN gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of LGTN gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of LGTN gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of LGTN gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing LGTN protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Experimental Protein Localization Evidence Scores cellular components containing LGTN protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with LGTN protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with LGTN gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DisGeNET Gene-Disease Associations diseases associated with LGTN gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells PubMedIDs of publications reporting gene signatures containing LGTN from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
GAD Gene-Disease Associations diseases associated with LGTN gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
GAD High Level Gene-Disease Associations diseases associated with LGTN gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of LGTN gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of LGTN gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of LGTN gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of LGTN gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of LGTN gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of LGTN gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for LGTN from the curated Hub Proteins Protein-Protein Interactions dataset.
KEA Substrates of Kinases kinases that phosphorylate LGTN protein from the curated KEA Substrates of Kinases dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of LGTN gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MiRTarBase microRNA Targets microRNAs targeting LGTN gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MSigDB Cancer Gene Co-expression Modules co-expressed genes for LGTN from the MSigDB Cancer Gene Co-expression Modules dataset.
NURSA Protein Complexes protein complexs containing LGTN protein recovered by IP-MS from the NURSA Protein Complexes dataset.
PFOCR Pathway Figure Associations 2024 pathways involving LGTN protein from the Wikipathways PFOCR 2024 dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of LGTN gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of LGTN protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of LGTN protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with LGTN protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.