| Name | LHFPL tetraspan subfamily member 7 |
| Description | Predicted to be active in membrane. [provided by Alliance of Genome Resources, Mar 2025] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A review of the provided abstracts reveals no direct functional characterization of LHFPL7. In one study of colorectal cancer transcriptomes (1), the expression of several novel genes was validated, with LHFPL7 possibly included among these candidates; however, no specific role was attributed to LHFPL7. Similarly, the olfactory (2) and taste organoid (3) transcriptome analyses did not provide functional insights regarding LHFPL7, as these works primarily focused on profiling receptor, signaling, and differentiation pathway genes. The remaining abstracts (4,5) neither mention nor discuss LHFPL7. Collectively, while LHFPL7 may have emerged during high‐throughput transcript profiling in these studies, its biological function remains uncharacterized based on the current data.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Citations:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bingjian Lü, Jing Xu, Maode Lai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A transcriptome anatomy of human colorectal cancers."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2407-6-40"}], "href": "https://doi.org/10.1186/1471-2407-6-40"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16504081"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16504081"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Ninthujah Kanageswaran, Marilen Demond, Maximilian Nagel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deep sequencing of the murine olfactory receptor neuron transcriptome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0113170"}], "href": "https://doi.org/10.1371/journal.pone.0113170"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25590618"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25590618"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Wenwen Ren, Eitaro Aihara, Weiwei Lei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome analyses of taste organoids reveal multiple pathways involved in taste cell generation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-04099-5"}], "href": "https://doi.org/10.1038/s41598-017-04099-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28638111"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28638111"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Thiago Vidotto, Daniel Guimarães Tiezzi, Jeremy A Squire "}, {"type": "b", "children": [{"type": "t", "text": "Distinct subtypes of genomic "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "PTEN"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " deletion size influence the landscape of aneuploidy and outcome in prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cytogenet (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13039-017-0348-y"}], "href": "https://doi.org/10.1186/s13039-017-0348-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29308088"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29308088"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Rupal L Shah, Jeremy A Guggenheim "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Genet (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00439-018-1942-8"}], "href": "https://doi.org/10.1007/s00439-018-1942-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30306274"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30306274"}]}]}]}
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| NCBI Gene ID | 255349 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LHFPL7 has 897 functional associations with biological entities spanning 5 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 12 datasets.
Click the + buttons to view associations for LHFPL7 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of LHFPL7 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of LHFPL7 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with LHFPL7 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of LHFPL7 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with LHFPL7 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of LHFPL7 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of LHFPL7 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of LHFPL7 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of LHFPL7 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of LHFPL7 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of LHFPL7 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with LHFPL7 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |