{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nDespite an extensive collection of abstracts covering receptor‐mediated innate immune and metabolic signaling—in contexts ranging from sterile inflammation and foam cell formation in atherosclerosis and Alzheimer’s disease to cancer‐associated immunometabolism and even aspects of viral entry—none of the studies directly address or mention LILRP2. In other words, while these articles elaborate on the functions of receptors such as CD36, Toll‐like receptors, TMPRSS2, and others (e.g."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": ", they do not provide any data or discussion regarding LILRP2.\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nThe compiled literature thoroughly details how receptor complexes and their co‐receptors—through ligand recognition, downstream signal transduction, and modulation of inflammatory or metabolic cascades—play key roles in disease pathogenesis. For instance, several studies highlight CD36’s function in binding oxidized lipids and amyloid‐beta to trigger inflammatory signaling cascades."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "12"}]}, {"type": "t", "text": " Other reports detail the interface between receptor signaling and metabolic reprogramming in immune cells that contribute to disease progression."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "13", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn summary, the collective evidence from these studies enriches our understanding of diverse receptor‐mediated regulatory mechanisms; however, they do not offer any insights into the function of LILRP2. The absence of explicit data on LILRP2 underscores an existing gap in the literature, suggesting that future investigations will be required to define the ligand specificity, signaling partners, and physiological roles of LILRP2 in health and disease."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "19", "end_ref": "26"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Cameron R Stewart, Lynda M Stuart, Kim Wilkinson, et al. 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