LINC00251 Gene

Name long intergenic non-protein coding RNA 251
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The provided abstracts do not contain any information regarding the function of LINC00251. In fact, while one study focused on genetic variants affecting bone mineral density (through genes such as"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "and another identified LINC<span style=\"font-weight:bold;\">01370</span> as a candidate susceptibility gene for idiopathic osteonecrosis of the femoral head"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ", there is no mention or discussion of LINC00251 in either work. Overall, these studies underscore the complex genetic regulation involved in bone-related disorders through both protein‐coding genes and noncoding RNAs; however, the function and role of LINC00251 remain unaddressed in the provided literature.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Benjamin H Mullin, John P Walsh, Hou-Feng Zheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Genomics (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12864-016-2481-0"}], "href": "https://doi.org/10.1186/s12864-016-2481-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26911590"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26911590"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Yuma Sakamoto, Takuaki Yamamoto, Nobuhiko Sugano, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-14778-y"}], "href": "https://doi.org/10.1038/s41598-017-14778-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29118346"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29118346"}]}]}]}
Synonyms C8ORF25, NCRNA00251
NCBI Gene ID 552859
API
Download Associations
Predicted Functions View LINC00251's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC00251's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC00251's ARCHS4 Predicted Functions.

Functional Associations

LINC00251 has 185 functional associations with biological entities spanning 3 categories (molecular profile, cell line, cell type or tissue, gene, protein or microRNA) extracted from 8 datasets.

Click the + buttons to view associations for LINC00251 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00251 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00251 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at LINC00251 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of LINC00251 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of LINC00251 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of LINC00251 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00251 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of LINC00251 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.