| Name | long intergenic non-protein coding RNA 343 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC00343, a long noncoding RNA, has been implicated in distinct pathological contexts through its altered expression. In glioblastoma, LINC00343 was identified within a lncRNA–miRNA–mRNA regulatory network and incorporated into prognostic risk prediction models alongside other key transcripts. Its dysregulation in this setting suggests a potential role in tumor pathogenesis and highlights its utility as a prognostic biomarker."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In a separate study of nonobstructive azoospermia, LINC00343 emerged as one of a panel of testis‐specific extracellular vesicle lncRNAs whose differential expression aids in predicting the presence of testicular spermatozoa. This panel offers a noninvasive approach to guide clinical decision‐making regarding sperm retrieval procedures."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiaomin Li, Rui Chen, Ci Ren, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Systematic analysis of the long noncoding RNA (lncRNA)-miRNA-mRNA competing endogenous RNA network to identify prognostic biomarkers and the potential regulatory axis in glioblastoma multiforme."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Transl Cancer Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21037/tcr-21-1162"}], "href": "https://doi.org/10.21037/tcr-21-1162"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35116328"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35116328"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Yun Xie, Jiahui Yao, Xinzong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A panel of extracellular vesicle long noncoding RNAs in seminal plasma for predicting testicular spermatozoa in nonobstructive azoospermia patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Reprod (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/humrep/deaa184"}], "href": "https://doi.org/10.1093/humrep/deaa184"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32914196"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32914196"}]}]}]}
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| Synonyms | NCRNA00343, NCRNA00344, LINC00344 |
| NCBI Gene ID | 144920 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC00343 has 188 functional associations with biological entities spanning 3 categories (disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 12 datasets.
Click the + buttons to view associations for LINC00343 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00343 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00343 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of LINC00343 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of LINC00343 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of LINC00343 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of LINC00343 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of LINC00343 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GWASdb SNP-Disease Associations | diseases associated with LINC00343 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
| GWASdb SNP-Phenotype Associations | phenotypes associated with LINC00343 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
| HuBMAP Azimuth Cell Type Annotations | cell types associated with LINC00343 gene from the HuBMAP Azimuth Cell Type Annotations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00343 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of LINC00343 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |