LINC00347 Gene

Name long intergenic non-protein coding RNA 347
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a genome‐wide association study performed on a Greek cohort, LINC00347 was identified as one of six long noncoding RNAs implicated in male infertility."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " The study revealed that LINC00347, through its interactions with microRNAs, may play a regulatory role in controlling the expression of genes essential for spermatogenesis and the fertilization process. Variations or polymorphisms on or near LINC00347 could disrupt these miRNA-mediated interactions, potentially leading to aberrant gene regulation and contributing to fertility issues. \n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Maria-Anna Kyrgiafini, Maria Markantoni, Theologia Sarafidou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study identifies candidate markers related to lincRNAs associated with male infertility in the Greek population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Assist Reprod Genet (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10815-020-01937-w"}], "href": "https://doi.org/10.1007/s10815-020-01937-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32880781"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32880781"}]}]}]}
NCBI Gene ID 338864
API
Download Associations
Predicted Functions View LINC00347's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC00347's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC00347's ARCHS4 Predicted Functions.

Functional Associations

LINC00347 has 283 functional associations with biological entities spanning 5 categories (molecular profile, organism, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 16 datasets.

Click the + buttons to view associations for LINC00347 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00347 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of LINC00347 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00347 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at LINC00347 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of LINC00347 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of LINC00347 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of LINC00347 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of LINC00347 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of LINC00347 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of LINC00347 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of LINC00347 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GWAS Catalog SNP-Phenotype Associations phenotypes associated with LINC00347 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
GWASdb SNP-Disease Associations diseases associated with LINC00347 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
GWASdb SNP-Phenotype Associations phenotypes associated with LINC00347 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00347 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of LINC00347 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.