LINC00364 Gene

Name long intergenic non-protein coding RNA 364
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC00364 is an interferon‐γ-induced long non-coding RNA that is downregulated in hepatocellular carcinoma tumor samples relative to adjacent normal tissue. Overexpression of LINC00364 in HCC cell lines has been shown to inhibit cell proliferation by arresting the cell cycle at the G1/S transition and to promote apoptosis, leading to a marked reduction in tumor formation. These findings suggest that LINC00364 acts as a tumor suppressor and may represent a promising therapeutic target in hepatocellular carcinoma."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Wei-Guo Tang, Bo Hu, Hai-Xiang Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long non-coding RNA00364 represses hepatocellular carcinoma cell proliferation via modulating p-STAT3-IFIT2 signaling axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.22039"}], "href": "https://doi.org/10.18632/oncotarget.22039"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29254221"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29254221"}]}]}]}
Synonyms LncRNA00364
NCBI Gene ID 100874145
API
Download Associations
Predicted Functions View LINC00364's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC00364's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC00364's ARCHS4 Predicted Functions.

Functional Associations

LINC00364 has 2 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 1 datasets.

Click the + buttons to view associations for LINC00364 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
GTEx Tissue Gene Expression Profiles tissues with high or low expression of LINC00364 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.