{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Although Abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "does not discuss LINC00388 explicitly, it provides insight into the general functions of long non-coding RNAs (lncRNAs) in the immune responses of teleost fish. In this context, lncRNAs—including LINC00388, by inference—are suggested to play key regulatory roles in immune modulation. They participate in multiple immune-related pathways such as the regulation of cytokine and chemokine signaling, antigen presentation, as well as complement and coagulation cascades, and T cell responses. Such regulation is critical for mounting appropriate responses to pathogenic infections in fish, which is pivotal given the economic and ecological impact of infectious diseases in aquaculture. Hence, while the precise functions of LINC00388 require further elucidation, its activities may mirror the broader roles observed for lncRNAs, thereby representing potential biomarkers and therapeutic targets for enhancing disease resistance in fish.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Man Wang, Shuai Jiang, Wei Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Non-coding RNAs Function as Immune Regulators in Teleost Fish."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Immunol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fimmu.2018.02801"}], "href": "https://doi.org/10.3389/fimmu.2018.02801"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30546368"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30546368"}]}]}]}