| Name | long intergenic non-protein coding RNA 548 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Our review of these abstracts reveals that none of the provided studies address the function or role of LINC00548. The first abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "reports a genome‐wide association study to identify novel susceptibility loci for antiphospholipid antibodies but does not mention LINC00548. Similarly, the second abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "focuses on characterizing long non‐coding RNAs in the cumulus–oocyte complex, identifying lncRNAs such as BCAR4, TUNAR, and LINC01118 among others, yet LINC00548 is not included in the identified set. The third abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": "describes advancements in gene targeting for therapeutic applications in hematopoietic stem cells and does not provide any data related to LINC00548.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, although these studies illuminate various aspects of lncRNA function in immunity, reproduction, and gene therapy, they do not provide insights into the biological role or mechanism of LINC00548. Further dedicated investigations are needed to elucidate the function of LINC00548 in biomedical contexts.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "M Ilyas Kamboh, Xingbin Wang, Amy H Kao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study of antiphospholipid antibodies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Autoimmune Dis (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2013/761046"}], "href": "https://doi.org/10.1155/2013/761046"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23509613"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23509613"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Julien Bouckenheimer, Patricia Fauque, Charles-Henri Lecellier, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Differential long non-coding RNA expression profiles in human oocytes and cumulus cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-018-20727-0"}], "href": "https://doi.org/10.1038/s41598-018-20727-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29396444"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29396444"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Begoña Diez, Pietro Genovese, Francisco J Roman-Rodriguez, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Therapeutic gene editing in CD34"}, {"type": "a", "children": [{"type": "t", "text": "sup"}], "href": "sup"}, {"type": "t", "text": "+"}, {"type": "a", "children": [{"type": "t", "text": "/sup"}], "href": "/sup"}, {"type": "t", "text": " hematopoietic progenitors from Fanconi anemia patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Mol Med (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15252/emmm.201707540"}], "href": "https://doi.org/10.15252/emmm.201707540"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28899930"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28899930"}]}]}]}
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| NCBI Gene ID | 400123 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC00548 has 175 functional associations with biological entities spanning 3 categories (disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 7 datasets.
Click the + buttons to view associations for LINC00548 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00548 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00548 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of LINC00548 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
| GWASdb SNP-Disease Associations | diseases associated with LINC00548 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
| GWASdb SNP-Phenotype Associations | phenotypes associated with LINC00548 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00548 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of LINC00548 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |