{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC00566 is a long non‐coding RNA identified as part of a three‐lncRNA signature that robustly stratifies ovarian cancer patients into high‐risk and low‐risk groups based on overall survival outcomes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In the study, LINC00566—along with KB-1836B5 and FAM27L—was selected from a set of 112 differentially expressed lncRNAs derived from The Cancer Genome Atlas data. The prognostic signature was shown to be independent of other clinical variables and its associated genes participated in metabolic processes and several key signaling pathways, including mechanistic target of rapamycin (mTOR) signaling, ubiquitin-mediated proteolysis, and the complement and coagulation cascades pathways. These findings suggest that LINC00566 may play a role in the regulation of oncogenic processes in ovarian cancer, thereby serving as a promising molecular biomarker for survival prediction."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Huijian Li, Mi Gong, Min Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNAs KB-1836B5, LINC00566 and FAM27L are associated with the survival time of patients with ovarian cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Lett (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ol.2018.9143"}], "href": "https://doi.org/10.3892/ol.2018.9143"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30127984"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30127984"}]}]}]}