| Name | long intergenic non-protein coding RNA 582 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent integrative lncRNA profiling in oral carcinoma revealed that LINC00582 is one of several long noncoding RNAs whose expression is significantly associated with patient outcomes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Unlike DUXAP8, whose functional role was further delineated through its interaction with the histone methyltransferase EZH2 and subsequent repression of KLF2—mechanisms that impact cancer cell proliferation"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "—the study did not provide specific mechanistic insights for LINC00582. Nonetheless, its statistical association with clinical outcomes suggests that LINC00582 may serve as a novel prognostic marker in oral carcinoma, warranting further investigation to elucidate its biological function.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mingwei Chen, Yanliang Zheng, Jingfang Xie, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrative profiling analysis identifies the oncogenic long noncoding RNA DUXAP8 in oral cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Anticancer Drugs (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/CAD.0000000000000936"}], "href": "https://doi.org/10.1097/CAD.0000000000000936"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32304409"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32304409"}]}]}]}
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| NCBI Gene ID | 100287814 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC00582 has 185 functional associations with biological entities spanning 4 categories (organism, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for LINC00582 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00582 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with LINC00582 gene from the CellMarker Gene-Cell Type Associations dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00582 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of LINC00582 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of LINC00582 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of LINC00582 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of LINC00582 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of LINC00582 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| HuBMAP Azimuth Cell Type Annotations | cell types associated with LINC00582 gene from the HuBMAP Azimuth Cell Type Annotations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC00582 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of LINC00582 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
