LINC00605 Gene

Name long intergenic non-protein coding RNA 605
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Based on the findings reported in"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", LINC00605 was identified as one of a panel of cancer‐specific long non‑coding RNAs significantly associated with overall survival in ovarian cancer patients. In this study, gene co‑expression network analyses—integrating competing endogenous RNA (ceRNA) and RNA binding protein‑mRNA interactions—revealed that LINC00605 is implicated in the molecular pathways underlying tumorigenesis. Its altered expression, as part of the identified lncRNA module, correlates with key clinical traits such as patient age, lymphatic and vascular invasion, and residual tumor disease, suggesting that LINC00605 may serve as a prognostic biomarker and potential therapeutic target in ovarian cancer.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Na Li, Xianquan Zhan "}, {"type": "b", "children": [{"type": "t", "text": "Identification of clinical trait-related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EPMA J (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13167-019-00175-0"}], "href": "https://doi.org/10.1007/s13167-019-00175-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31462944"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31462944"}]}]}]}
NCBI Gene ID 100131366
API
Download Associations
Predicted Functions View LINC00605's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC00605's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC00605's ARCHS4 Predicted Functions.

Functional Associations

LINC00605 has 362 functional associations with biological entities spanning 3 categories (disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 9 datasets.

Click the + buttons to view associations for LINC00605 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00605 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00605 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of LINC00605 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of LINC00605 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of LINC00605 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of LINC00605 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of LINC00605 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00605 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of LINC00605 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.