{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A review of the provided abstracts does not reveal any direct mention or investigation of LINC00698. Instead, the abstracts focus on other long noncoding RNAs (lncRNAs) and their roles in cancer and cellular regulation. For instance, one study demonstrates how the oncogenic lncRNA SAMMSON simultaneously modulates cytosolic and mitochondrial translation by altering the cellular localization of RNA‐binding proteins to promote rRNA maturation and protein synthesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Another investigation characterizes dysregulated lncRNAs that function within a competing endogenous RNA (ceRNA) network involved in the tumorigenesis and progression of muscle‐invasive bladder cancer, although LINC00698 was not among the lncRNAs identified."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " A third study uses a computational pipeline (SNIPER) to highlight the potential disease‐causing impact of single-nucleotide variations on the secondary structures of several untranslated regions and lncRNAs, further underscoring the role of RNA structure in cancer genomes without reference to LINC00698."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " Finally, another genome-wide association study identifies genetic loci influencing serum mineral element levels and reports novel lncRNA-associated loci; however, this work focuses on different lncRNAs (for example, loci in LINC00908-LINC00683) without specifically addressing LINC00698."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, while these studies collectively highlight the multifaceted roles of lncRNAs in the regulation of translation, cancer progression, and metabolic functions, none of them provide insights into the function of LINC00698. Further research will be required to elucidate whether LINC00698 plays similar or distinct roles in these biological processes.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Roberto Vendramin, Yvessa Verheyden, Hideaki Ishikawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Struct Mol Biol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41594-018-0143-4"}], "href": "https://doi.org/10.1038/s41594-018-0143-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30374086"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30374086"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Hanbo Wang, Leilei Niu, Shaobo Jiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle-invasive bladder cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.13363"}], "href": "https://doi.org/10.18632/oncotarget.13363"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27863388"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27863388"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Funan He, Ran Wei, Zhan Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrative Analysis of Somatic Mutations in Non-coding Regions Altering RNA Secondary Structures in Cancer Genomes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-44489-5"}], "href": "https://doi.org/10.1038/s41598-019-44489-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31160636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31160636"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Duojian Guo, Yu Zhou, Xingwei Wei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Preliminary study of genome-wide association identifies novel susceptibility genes for serum mineral elements in the Chinese Han population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Trace Elem Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12011-021-02854-4"}], "href": "https://doi.org/10.1007/s12011-021-02854-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34417961"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34417961"}]}]}]}