{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a study profiling RNA‐seq data during the transition from human embryonic stem cells to multipotential cardiovascular progenitors and further specialized cardiovascular lineages, a novel computational method (GEPA) enabled the identification of dynamically expressed RNAs, including a subset of lineage‐enriched long non‐coding RNAs. Among these, LINC00881 was identified as a candidate regulatory RNA that exhibits stage‐ and lineage‐specific expression during early heart development. Its expression pattern suggests that LINC00881 may contribute to the intricate regulatory network governing the differentiation of cardiovascular progenitors into cardiomyocytes and other cardiovascular cell types, potentially by modulating transcriptional and post‐transcriptional mechanisms critical for precise heart formation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yang Li, Bo Lin, Lei Yang "}, {"type": "b", "children": [{"type": "t", "text": "Comparative transcriptomic analysis of multiple cardiovascular fates from embryonic stem cells predicts novel regulators in human cardiogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/srep09758"}], "href": "https://doi.org/10.1038/srep09758"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25997157"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25997157"}]}]}]}