{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Long non‐coding RNAs (lncRNAs) are increasingly recognized as key regulators in both normal biology and disease. In a recent study of cervical cancer recurrence, LINC00905 was identified as one of several lncRNAs whose high expression was significantly associated with poorer recurrence‐free survival. In this work, based on TCGA data analysis and Cox regression modeling, elevated LINC00905 levels contributed to a recurrence risk score (RRS) that effectively stratified patients with a higher risk of tumor relapse. These findings suggest that LINC00905 may serve as a prognostic biomarker and might play a functional role in promoting an aggressive cervical cancer phenotype. Although other studies have emphasized the diverse functions of non‐coding sequences—ranging from the contribution of retroposed elements to gene evolution in primates"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "to the emerging involvement of piRNAs in neurodegenerative disorders such as Alzheimer’s disease"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "—the cervical cancer study highlights a specific clinical context in which LINC00905 is directly linked to adverse outcomes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Robert Baertsch, Mark Diekhans, W James Kent, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Retrocopy contributions to the evolution of the human genome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Genomics (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2164-9-466"}], "href": "https://doi.org/10.1186/1471-2164-9-466"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18842134"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18842134"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Wenying Qiu, Xiaoyun Guo, Xiandong Lin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurobiol Aging (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neurobiolaging.2017.05.020"}], "href": "https://doi.org/10.1016/j.neurobiolaging.2017.05.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28654860"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28654860"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Yan Zhang, Xing Zhang, Haixia Zhu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Recurrence in Patients with Cervical Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Manag Res (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2147/CMAR.S231796"}], "href": "https://doi.org/10.2147/CMAR.S231796"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32099468"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32099468"}]}]}]}