LINC00911 Gene

Name long intergenic non-protein coding RNA 911
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Genome‐wide studies in chronic obstructive pulmonary disease (COPD) (1) and blood lipid traits (3) have advanced our understanding of the genetic architecture underlying complex diseases, yet did not specifically implicate LINC00911. In contrast, transcriptomic profiling across breast cancer subtypes (2) revealed that among several dysregulated long noncoding RNAs, LINC00911 is notably overexpressed in triple‐negative breast cancers. High LINC00911 expression was associated with poorer survival outcomes in this aggressive subtype, suggesting that it may play an oncogenic or disease‐promoting role. These findings highlight LINC00911 as a potential prognostic biomarker and underscore the need for further investigation into its mechanistic contributions to breast cancer progression.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Citations:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Louise V Wain, Nick Shrine, María Soler Artigas, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.3787"}], "href": "https://doi.org/10.1038/ng.3787"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28166213"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28166213"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xiao-Xiao Li, Li-Juan Wang, Jie Hou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of Long Noncoding RNAs as Predictors of Survival in Triple-Negative Breast Cancer Based on Network Analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Res Int (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2020/8970340"}], "href": "https://doi.org/10.1155/2020/8970340"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32190687"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32190687"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Prashantha Hebbar, Rasheeba Nizam, Motasem Melhem, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Lipid Res (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1194/jlr.P080218"}], "href": "https://doi.org/10.1194/jlr.P080218"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30108155"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30108155"}]}]}]}
NCBI Gene ID 100996280
API
Download Associations
Predicted Functions View LINC00911's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC00911's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC00911's ARCHS4 Predicted Functions.

Functional Associations

LINC00911 has 20 functional associations with biological entities spanning 2 categories (cell line, cell type or tissue, gene, protein or microRNA) extracted from 5 datasets.

Click the + buttons to view associations for LINC00911 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC00911 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of LINC00911 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of LINC00911 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue-Specific Aging Signatures tissue samples with high or low expression of LINC00911 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of LINC00911 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.