{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Several recent studies have underscored the potential clinical relevance of long non‐coding RNAs in human diseases."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In particular, LINC00938 has emerged as a candidate biomarker across distinct pathological contexts. In non‐small cell lung cancer, LINC00938 was found to be among the dysregulated lncRNAs whose altered expression was significantly associated with overall patient survival, suggesting a potential role in tumor progression and prognostication."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " In a separate study focused on Parkinson disease, LINC00938 was observed to be up‐regulated in peripheral blood mononuclear cells from patients, and mechanistic experiments demonstrated that it acts as a competing endogenous RNA by directly sponging hsa‐miR‑30c‑5p. This interaction is implicated in regulating the expression of key PD-related genes, such as LRRK2 and ATP13A2, thereby contributing to disease pathogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Fuduan Peng, Ruiping Wang, Yuanyuan Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12943-017-0666-z"}], "href": "https://doi.org/10.1186/s12943-017-0666-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28587642"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28587642"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Mingjie Zhu, Qing Lv, Hu Huang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a four-long non-coding RNA signature in predicting breast cancer survival."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Lett (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ol.2019.11063"}], "href": "https://doi.org/10.3892/ol.2019.11063"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31897133"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31897133"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Wenyong Zhou, Tao Liu, Gaowa Saren, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive analysis of differentially expressed long non-coding RNAs in non-small cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Lett (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ol.2019.10414"}], "href": "https://doi.org/10.3892/ol.2019.10414"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31423174"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31423174"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Maryam Yousefi, Maryam Peymani, Kamran Ghaedi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Significant modulations of linc001128 and linc0938 with miR-24-3p and miR-30c-5p in Parkinson disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-022-06539-3"}], "href": "https://doi.org/10.1038/s41598-022-06539-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35173238"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35173238"}]}]}]}