| Name | long intergenic non-protein coding RNA 1000 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n After review of the five abstracts"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": ", it is evident that none of these studies mention or investigate an lncRNA designated as LINC01000. Instead, the reports focus on other non‐coding RNAs and genomic alterations involved in diverse pathological and cellular contexts. For example, one study on hepatosplenic T‐cell lymphoma attributed oncogenic effects to chromosomal imbalances that affect genes such as CHN2 and ABCB1 (1), while another study in nasopharyngeal carcinoma detailed the tumor‐promoting actions of lncRNA ZFAS1 through a microRNA-mediated mechanism (2). Additional work examined sex‐specific transcriptomic changes in tendon pathobiology (3), identified novel lncRNAs associated with the metastasis‐promoting phenotype of ovarian cancer-associated fibroblasts (4), and described a unique spontaneous conversion of skin fibroblasts into keratinocyte-like cells (5). As no findings related to LINC01000 were reported in these contexts, its function remains undetermined based on the provided abstracts.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Julio Finalet Ferreiro, Leila Rouhigharabaei, Helena Urbankova, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0102977"}], "href": "https://doi.org/10.1371/journal.pone.0102977"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25057852"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25057852"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Jiaojiao Peng, Feng Liu, Hong Zheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long noncoding RNA ZFAS1 promotes tumorigenesis and metastasis in nasopharyngeal carcinoma by sponging miR-892b to up-regulate LPAR1 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Mol Med (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/jcmm.14823"}], "href": "https://doi.org/10.1111/jcmm.14823"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31851778"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31851778"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Louise I Pease, Peter D Clegg, Carole J Proctor, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-14650-z"}], "href": "https://doi.org/10.1038/s41598-017-14650-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29089527"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29089527"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Fatemeh Vafaee, Emily K Colvin, Samuel C Mok, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional prediction of long non-coding RNAs in ovarian cancer-associated fibroblasts indicate a potential role in metastasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-10869-y"}], "href": "https://doi.org/10.1038/s41598-017-10869-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28871211"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28871211"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Fang Zhang, Dandan Zhang, Kai Cheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Spontaneous evolution of human skin fibroblasts into wound-healing keratinocyte-like cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Theranostics (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7150/thno.31526"}], "href": "https://doi.org/10.7150/thno.31526"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31410210"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31410210"}]}]}]}
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| NCBI Gene ID | 402483 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC01000 has 491 functional associations with biological entities spanning 3 categories (functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 9 datasets.
Click the + buttons to view associations for LINC01000 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LINC01000 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of LINC01000 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LINC01000 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01000 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of LINC01000 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of LINC01000 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01000 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of LINC01000 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain LINC01000 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |