LINC01023 Gene

Name long intergenic non-protein coding RNA 1023
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Linc01023 is significantly overexpressed in glioma tissues and cell lines, and its increased expression is associated with shorter patient survival."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Functional studies indicate that silencing linc01023 restrains glioma cell proliferation, migration, and invasion by modulating the IGF1R/AKT signaling pathway. These findings position linc01023 as an oncogenic factor in glioma and highlight its potential as a therapeutic target.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mingjun Yu, Shijia Yu, Wei Gong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Knockdown of linc01023 restrains glioma proliferation, migration and invasion by regulating IGF-1R/AKT pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7150/jca.31004"}], "href": "https://doi.org/10.7150/jca.31004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31281473"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31281473"}]}]}]}
Synonyms HP07349
NCBI Gene ID 100652853
API
Download Associations
Predicted Functions View LINC01023's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC01023's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC01023's ARCHS4 Predicted Functions.

Functional Associations

LINC01023 has 306 functional associations with biological entities spanning 2 categories (chemical, cell line, cell type or tissue) extracted from 5 datasets.

Click the + buttons to view associations for LINC01023 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC01023 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of LINC01023 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of LINC01023 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC01023 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of LINC01023 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.