{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A recent bioinformatics investigation into the molecular basis of peritoneal metastasis in gastric cancer identified several long non‐coding RNAs, including LINC01151 (NR_126348), that are up‐regulated when gastric cancer cells are co‐cultured with adipocytes to mimic the peritoneal microenvironment."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Although the study primarily highlighted the prognostic relevance and immune associations of another lncRNA (LINC00924), the concurrent up‐regulation of LINC01151 suggests that it may also play a role in the metastatic process. Its expression pattern in the adipocyte co‐culture model implies that LINC01151 could be involved in mediating tumor–stromal interactions or metabolic adaptations that facilitate peritoneal dissemination in gastric cancer. Further functional characterization is needed to determine the precise mechanisms by which LINC01151 may contribute to tumor progression and metastasis.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yan Fang, Sihao Huang, Lei Han, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive Analysis of Peritoneal Metastasis Sequencing Data to Identify LINC00924 as a Prognostic Biomarker in Gastric Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Manag Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2147/CMAR.S318704"}], "href": "https://doi.org/10.2147/CMAR.S318704"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34285580"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34285580"}]}]}]}