| Name | long intergenic non-protein coding RNA 1160 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent findings indicate that LINC01160, a long non‐coding RNA, plays a significant role in modulating key cellular processes associated with cancer progression. In particular, data from"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "suggest that aberrant overexpression of LINC01160 is correlated with enhanced cell proliferation, migration, and invasion. Mechanistic investigations propose that LINC01160 may function as a competing endogenous RNA (ceRNA) by binding and sequestering specific microRNAs, which in turn leads to the de‐repression of oncogenic targets and subsequent activation of pro‐tumorigenic pathways. This functional characterization not only highlights LINC01160 as a contributor to the aggressive phenotype observed in tumor cells but also underscores its potential as a prognostic biomarker and therapeutic target in oncology.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jingang Ai, Guolin Tan, Tiansheng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcription factor STAT1 promotes the proliferation, migration and invasion of nasopharyngeal carcinoma cells by upregulating "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "LINC01160"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": "."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Future Oncol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2217/fon-2020-0618"}], "href": "https://doi.org/10.2217/fon-2020-0618"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33263259"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33263259"}]}]}]}
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| NCBI Gene ID | 100129269 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC01160 has 155 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 3 datasets.
Click the + buttons to view associations for LINC01160 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01160 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with LINC01160 gene from the CellMarker Gene-Cell Type Associations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01160 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |