{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The study summarized in the abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "presents a comprehensive analysis of transcriptomic changes—including differential splicing and gene expression—in brain samples from individuals with major psychiatric disorders. The work integrates genotypic and RNA sequencing data to uncover disease-associated alterations across the transcriptome and link them to genetic risk. However, within this abstract no explicit functional role for LINC01166 is described. In other words, while the study focuses on broad regulatory changes and prioritizes disease loci that may mediate pathogenic cis effects on brain expression, there is no direct information provided that delineates the specific function or impact of LINC01166 in these processes.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Michael J Gandal, Pan Zhang, Evi Hadjimichael, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.aat8127"}], "href": "https://doi.org/10.1126/science.aat8127"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30545856"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30545856"}]}]}]}