{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a recent study on papillary thyroid cancer (PTC), LINC01176 was identified as one of nine key long non-coding RNAs (lncRNAs) that together form a robust signature with significant diagnostic and prognostic value (1). Functional enrichment analyses, including Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment analysis, implicated this lncRNA signature in several biological processes and signaling pathways involved in PTC tumorigenesis. Notably, the levels of LINC01176—and the other hub lncRNAs—were correlated with the distribution of tumor-infiltrating immune cells, suggesting that LINC01176 may play a role in modulating the tumor immune microenvironment. The integration of LINC01176 into a multi-lncRNA model further underscores its potential as a biomarker for improving both the prognosis and diagnosis of PTC."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jin-Ming Yao, Jun-Yu Zhao, Fang-Fang Lv, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Potential Nine-lncRNAs Signature Identification and Nomogram Diagnostic Model Establishment for Papillary Thyroid Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Oncol Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/pore.2022.1610012"}], "href": "https://doi.org/10.3389/pore.2022.1610012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35280112"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35280112"}]}]}]}