| Name | long intergenic non-protein coding RNA 1194 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A careful review of the 50 provided abstracts reveals that none of these studies describe, mention, or characterize any function for the long noncoding RNA LINC01194. Instead, the abstracts focus on a wide spectrum of molecules and cellular processes—including regulators of oncogenic signaling (such as microRNA‐21, HDAC6, and EGR1), adaptor and transport proteins (for example, AP‐4 and BRAP2), metabolic enzymes (like succinate dehydrogenase), viral oncoproteins (from polyomaviruses and JC virus), as well as components of immune and stress responses—and their roles in tumorigenesis, signal transduction, cell survival, and host defense (see, for example"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": ", and."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Because none of the abstracts provide experimental or mechanistic insights regarding LINC01194, no conclusions can be drawn from this body of literature about its biological role or clinical relevance. This indicates that, at least in the context of these studies, LINC01194 remains uncharacterized. Clarification of its function will require data from dedicated investigations focused specifically on LINC01194.\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, while the abstracts collectively enhance our understanding of diverse molecular processes in cancer, viral infection, immunity, and cellular stress (as supported by"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "9"}]}, {"type": "t", "text": ", and"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": "among others), none of them address LINC01194. Future research specifically targeting LINC01194 is needed to uncover whether it plays a role in any of these processes.\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n (1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50)\n "}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n <!-- Hyperlinks for each PMID -->\n <small>"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "50"}]}, {"type": "t", "text": "</small>\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mark E Hatley, David M Patrick, Matthew R Garcia, et al. 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| Synonyms | CT49, TAG |
| NCBI Gene ID | 404663 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC01194 has 342 functional associations with biological entities spanning 4 categories (molecular profile, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for LINC01194 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01194 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at LINC01194 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of LINC01194 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of LINC01194 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of LINC01194 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GWASdb SNP-Disease Associations | diseases associated with LINC01194 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
| GWASdb SNP-Phenotype Associations | phenotypes associated with LINC01194 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
| Hub Proteins Protein-Protein Interactions | interacting hub proteins for LINC01194 from the curated Hub Proteins Protein-Protein Interactions dataset. | |
| HuGE Navigator Gene-Phenotype Associations | phenotypes associated with LINC01194 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01194 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at LINC01194 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |