LINC01208 Gene

Name long intergenic non-protein coding RNA 1208
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a study aimed at constructing a prognostic model for breast cancer, LINC01208 was identified as one of ten long noncoding RNAs whose differential expression was associated with patient survival (1). Although the study did not provide mechanistic details on LINC01208, its inclusion in the signature model—along with nine other lncRNAs—underscores its potential as a prognostic biomarker in breast cancer. The constructed model, which stratified patients based on a risk score derived from multivariate Cox regression analysis, demonstrated robust predictive performance with a C-index of 0.712 and respectable AUC scores, suggesting that the expression level of LINC01208 may reflect key aspects of tumor biology that impact overall survival (1). Overall, LINC01208 appears to serve as an integral component of a multi-lncRNA signature that can aid in the prognostication of breast cancer outcomes."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Wenqing Zhou, Yongkui Pang, Yunmin Yao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Development of a Ten-lncRNA Signature Prognostic Model for Breast Cancer Survival: A Study with the TCGA Database."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Anal Cell Pathol (Amst) (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2020/6827057"}], "href": "https://doi.org/10.1155/2020/6827057"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32908814"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32908814"}]}]}]}
NCBI Gene ID 100505547
API
Download Associations
Predicted Functions View LINC01208's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC01208's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC01208's ARCHS4 Predicted Functions.

Functional Associations

LINC01208 has 109 functional associations with biological entities spanning 2 categories (cell line, cell type or tissue, gene, protein or microRNA) extracted from 3 datasets.

Click the + buttons to view associations for LINC01208 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of LINC01208 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of LINC01208 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of LINC01208 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.