{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC01254 is one of several long non‐coding RNAs whose expression has been implicated in the progression of acute coronary syndromes. In a study profiling 2,332 lncRNAs in patients with myocardial infarction (MI) and unstable angina (UA), LINC01254 was identified among a panel of 7 candidate biomarkers that distinguished MI from UA with high accuracy (90.38% overall, 100% sensitivity)."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Functional analyses of these lncRNAs suggested that they are involved in biological processes and pathways that are intimately associated with MI pathogenesis, hinting that LINC01254 may play a regulatory role in orchestrating gene networks underlying cardiovascular disease progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Together, these findings indicate that LINC01254 not only serves as a promising diagnostic biomarker to help differentiate between MI and UA but may also be functionally involved in the molecular mechanisms leading to myocardial infarction.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yingjie Lu, Xiangwei Meng, Lifeng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Analysis of long non-coding RNA expression profiles identifies functional lncRNAs associated with the progression of acute coronary syndromes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Ther Med (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/etm.2017.5573"}], "href": "https://doi.org/10.3892/etm.2017.5573"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29434722"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29434722"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Aining Chu, Jingwei Liu, Yuan Yuan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive Analysis of Aberrantly Expressed ceRNA network in gastric cancer with and without "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "H.pylori"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7150/jca.27803"}], "href": "https://doi.org/10.7150/jca.27803"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30854091"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30854091"}]}]}]}