{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Among the abstracts provided, only one (Abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "discusses a long non‐coding RNA in a genomic region altered by a balanced translocation associated with mild intellectual deficiency. In that study, the translocation breakpoint on chromosome 5 lies 228 kb upstream of the MEF2C gene within a topologically associated domain that also contains a long non-coding RNA (named LINC01226). Although this abstract does not detail a specific molecular function for the long non‐coding RNA, its genomic inclusion in the MEF2C-containing TAD implies it could be part of a regulatory network influencing MEF2C expression. However, no direct functional role for LINC01266 (or a similarly named transcript) is described in any of these studies. The other abstracts"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ", and"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": "focus on other aspects of circulating RNAs, copy-number variations in neurodevelopmental disorders, and transcriptomic changes in multiple sclerosis, respectively, without providing additional insights into the function of LINC01266."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, while a long non-coding RNA (specifically LINC01226) is mentioned in the context of a disrupted genomic region potentially affecting MEF2C expression (Abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", there is no direct evidence or discussion provided regarding the function of LINC01266 across these studies.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Kevin Yauy, Anouck Schneider, Bee Ling Ng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Disruption of chromatin organisation causes MEF2C gene overexpression in intellectual disability: a case report."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Med Genomics (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12920-019-0558-8"}], "href": "https://doi.org/10.1186/s12920-019-0558-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31375103"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31375103"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Anna V Savelyeva, Elena V Kuligina, Dmitry N Bariakin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variety of RNAs in Peripheral Blood Cells, Plasma, and Plasma Fractions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Res Int (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2017/7404912"}], "href": "https://doi.org/10.1155/2017/7404912"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28127559"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28127559"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Tiago Fernando Chaves, Nathacha Baretto, Luan Freitas de Oliveira, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Copy Number Variations in a Cohort of 420 Individuals with Neurodevelopmental Disorders From the South of Brazil."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-54347-z"}], "href": "https://doi.org/10.1038/s41598-019-54347-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31780800"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31780800"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Lucas Schirmer, Dmitry Velmeshev, Staffan Holmqvist, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Neuronal vulnerability and multilineage diversity in multiple sclerosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41586-019-1404-z"}], "href": "https://doi.org/10.1038/s41586-019-1404-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31316211"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31316211"}]}]}]}