{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC01300 is a long noncoding RNA that has been implicated in the modulation of oncogenic processes. In particular, experimental evidence indicates that aberrant levels of LINC01300 are associated with enhanced cell proliferation, invasion, and overall tumor progression. Mechanistic studies reveal that LINC01300 acts as a competing endogenous RNA, sequestering specific microRNAs and thereby de‐repressing target oncogenes that regulate the cell cycle and metastatic potential. This ceRNA activity underscores its role in balancing gene expression networks that drive malignant transformation, highlighting LINC01300 not only as a key player in tumorigenesis but also as a potential biomarker for prognosis and therapeutic targeting."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bowen Yang, Jiming Shen, Lu Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-Wide Identification of a Novel Eight-lncRNA Signature to Improve Prognostic Prediction in Head and Neck Squamous Cell Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Oncol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fonc.2019.00898"}], "href": "https://doi.org/10.3389/fonc.2019.00898"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31620361"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31620361"}]}]}]}