{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a study aimed at constructing a predictive signature based on autophagy‐associated lncRNAs for lung adenocarcinoma (LUAD), LINC01338 was identified as one of 13 differentially expressed lncRNAs that correlate with autophagy‐related genes in tumor samples. The inclusion of LINC01338 in this signature—developed from a comparative analysis between LUAD tissues and normal lung tissues—suggests that it may play a role in regulating autophagy‐related mechanisms that impact tumor progression. Moreover, its differential expression contributes to stratifying patients into high‐risk versus low‐risk groups, which was strongly associated with overall survival outcomes. This finding supports the potential use of LINC01338, along with the other lncRNAs in the signature, as a prognostic biomarker in LUAD, providing further insight into the molecular underpinnings of autophagy in cancer prognosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mi Zhou, Weihua Shao, Haiyun Dai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Robust Signature Based on Autophagy-Associated LncRNAs for Predicting Prognosis in Lung Adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Res Int (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2020/3858373"}], "href": "https://doi.org/10.1155/2020/3858373"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32190662"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32190662"}]}]}]}